Publications
Brain Registration and Evaluation for Zebrafish (BREEZE)-mapping: A pipeline for whole-brain structural and activity analyses
Jin DS**, Neelakantan U**, Lacadie CM, Chen T, Rooney B, Liu Y, Wu W, Wang Z, Papademetris X, Hoffman EJ*. STAR Protoc. 2023 Dec 15;4(4):102647.
doi: 10.1016/j.xpro.2023.102647. Epub 2023 Oct 26.PMID: 37897734
High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.
Weinschutz Mendes H, Neelakantan U, Liu Y, Fitzpatrick SE, Chen T, Wu W, Pruitt A, Jin DS, Jamadagni P, Carlson M, Lacadie CM, Enriquez KD, Li N, Zhao D, Ijaz S, Sakai C, Szi C, Rooney B, Ghosh M, Nwabudike I, Gorodezky A, Chowdhury S, Zaheer M, McLaughlin S, Fernandez JM, Wu J, Eilbott JA, Vander Wyk B, Rihel J, Papademetris X, Wang Z, Hoffman EJ*. Cell Reports 2023; 42(3):112243. Epub 20230316.
doi: 10.1016/j.celrep.2023.112243.
Zebrafish Mutants of Autism Risk Genes
Estrogens suppress a behavioral phenotype in zebrafish mutants of the autism risk gene, CNTNAP2.
Hoffman, EJ, Turner, KJ, Fernandez, JM, Cifuentes, D, Ghosh, M, Ijaz, S., Jain, RA, Kubo, F, Baier, H, Granato, M, Barresi, MJF, Wilson, SW, Rihel, R, State, MW, Giraldez AJ.
Neuron. 2016 Feb 17;89(4):725-33.
Zebrafish: A Translational Model System for Studying Neuropsychiatric Disorders.
Ijaz, S., Hoffman, EJ.
J Am Acad Child Adolesc Psychiatry. 2016 Sep; 55(9):746-8.
Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future
Sakai, C., Ijaz, S., Hoffman, EJ.
Front Mol Neurosci. 2018 Aug 29; 11: 294
Autism Genetics
Methods of Generating Zebrafish Mutants
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.
Willsey AJ, Sanders SJ, Li M, Dong S, Tebbenkamp AT, Muhle RA, Reilly SK, Lin L, Fertuzinhos S, Miller JA, Murtha MT, Bichsel C, Niu W, Cotney J, Ercan-Sencicek AG, Gockley J, Gupta AR, Han W, He X, Hoffman EJ, Klei L, Lei J, Liu W, Liu L, Lu C, Xu X, Zhu Y, Mane SM, Lein ES, Wei L, Noonan JP, Roeder K, Devlin B, Sestan N, State MW. Cell 2013 Nov 21;155(5):997-1007. PMID: 24267886.
Progress in cytogenetics: implications for child psychopathology.
Hoffman EJ & State MW.
J. Am. Acad. Child Adolesc. Psychiatry 2010;49(8):736-51; quiz 856-7. PMID: 20643309
A large-scale screen for coding variants in SERT/1 SLC6A4 in autism.
Sakurai, T, Reichert, J, Hoffman, EJ, Cai, G, Jones, HB, Faham, M, & Buxbaum, JD.
Autism Res. 2008 1 (4): 251-257. PMID: 1936067
Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: Efficient identification of known microduplications and identification of a novel microduplication in ASMT.
Cai G, Edelmann L, Goldsmith JE, Cohen N, Nakamine A, Reichert JG, Hoffman EJ, Zurawiecki DM, Silverman JM, Hollander E, Soorya L, Anagnostou E, Betancur C, Buxbaum JD.
BMC Med Genomics. 2008 Oct 16; 1: 50. PMID: 18925931
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).
Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK.
Nat. Methods 2011 Jan;8(1):67-9. PMID: 21151135
Neuroscience and Psychiatry
Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons.
Hoffman EJ, Mintz CD, Wang S, McNickle DG, Salton SR, Benson DL.
Neuroscience. 2008 Dec 2; 157 (3):556-65. PMID: 18926887
Anxiety disorders: a comprehensive review of pharmacotherapies.
Hoffman EJ, Mathew SJ.
Mt Sinai J Med. 2008 May-Jun; 75 (3): 248-62. PMID: 18704983
Clinical Features and Diagnosis of Autism and Other Pervasive Developmental Disorders
Hoffman EJ
Primary Psychiatry 2009; 16 (1): 36-44
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